Searchable abstracts of presentations at key conferences in endocrinology

ea0059oc1.3 | Translational highlights | SFEBES2018

Novel insights into the genetic architecture of thyroid disease

Taylor Peter , Anney Richard , Dayan Colin , Ludgate Marian , Rees Aled

Introduction: There has been a substantial increase in our knowledge of the genetic architecture of thyroid function, with numerous variants associated with TSH and/or FT4 levels. However, our knowledge of the genetic variants associated with thyroid disease is more limited.Methods: Data was obtained from the Neale laboratory† which provided a case-control study to identify single nucleotide polymorphisms associated with a diagnosis of hypothyroidi...